SCHEMBL49088

SCHEMBL49088

CO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.41
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 3/20 0.35
LTA4H P09960 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 4/20 0.33
MAPK1 P28482 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705043 0.97 ESR1 (0.41) CA4ESR1ESR2CA12CA1
SCHEMBL3482517 0.88 ACHE (0.43) CA4ESR1ESR2POLBALDH1A1
SCHEMBL5416836 0.88 ESR1 (0.35) CA4ESR1ESR2POLB
SCHEMBL8636462 0.87 CA4 (0.36) CA4ESR1ESR2CA12CA1
SCHEMBL15863734 0.86 CA4 (0.32) CA4ESR1ESR2
SCHEMBL3481484 0.84 LMNA (0.35) CA4ALDH1A1TSHRMAPK1LMNA
SCHEMBL3482513 0.82 TP53 (0.50) POLBALDH1A1LTA4HCYP1A2CYP2C19
SCHEMBL7746293 0.81 TSHR (0.31) LTA4HTSHR
SCHEMBL15066840 0.81 CYP2A6 (0.45) CA1CA2CA7CA9ALDH1A1
SCHEMBL24390119 0.79 LTA4H (0.45) CA4ALDH1A1LTA4HTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2154 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574290-A Preparation method of ultra-high-toughness 4-methyl-1-pentene/alpha-olefin copolymer 万华化学集团股份有限公司 2026-02-27 CN claimed
CN-120041084-A Organosilicon coating and preparation method and application thereof 广东美的制冷设备有限公司 2025-05-27 CN claimed
US-12312494-B2 Resin composition, method for producing same, and multi-liquid curable resin composition KANEKA CORPORATION (JP) 2025-05-27 US claimed
CN-119786724-A Electrolyte additive, electrolyte and battery 江苏正力新能电池技术股份有限公司 2025-04-08 CN claimed
CN-119613968-A Low-viscosity high-transparency liquid silicone rubber and preparation method thereof 湖北兴瑞硅材料有限公司 2025-03-14 CN claimed
CN-119552510-A High-refractive-index low-haze addition type liquid silicone rubber and preparation method thereof 湖北兴瑞硅材料有限公司 2025-03-04 CN claimed
US-20250011621-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2025-01-09 US claimed
CN-118988237-A Device for continuously producing phenylsilane and preparation method 江西宏柏新材料股份有限公司 2024-11-22 CN claimed
US-20240309144-A1 SILANE MODIFIED ALIPHATIC POLYUREA EVONIK OPERATIONS GMBH (DE) 2024-09-19 US claimed
CN-118560082-A Method for integrally preparing liquid crystal polyarylester nanofiber composite paper honeycomb through thermal welding and gum dipping 武汉纺织大学 2024-08-30 CN claimed
US-20030027711-A1 Clay-titanium tetrachloride catalyst and the preparation thereof CHANGCHUN INSTITUTE OF APLLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2003-02-06 US claimed
CN-1330101-A Montmorillonite-TiCl4 catalyst and process for preparing polyolefin/montmorillonite composition CHANGCHUN APPLIED CHEMISTRY (CN) 2002-01-09 CN claimed
US-6323148-B1 MADE BY CONTACTING IN SEVERAL DIFFERENT ORDERS TRIALKYLAMINE; TETRAHYDROCARBYLOXYTITANIUM; DIALKYLMAGNESIUM COMPOUND OR COMPLEX; ALCOHOL OR OXYSILANE COMPOUND; AND TRANSITION METAL COMPOUND; FOR MAKING LINEAR LOW DENSITY ETHYLENE POLYMERS EQUISTAR CHEMICALS, LP 2001-11-27 US claimed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP claimed
US-6017995-A AN AQUEOUS SUSPENSION COMPRISING MICA, AT LEAST ONE SILANE, A POLYSILOXANE, A COMPOUND CATALYZING THE HYDROLYSIS AND/OR COUPLING REACTION AND ADDITIVES; IMPROVING THE FORMED SHEET MECHANICAL AND ELECTRICAL PROPERTIES WACKER-CHEMIE GMBH (DE) 2000-01-25 US claimed
EP-0457175-B1 Method of purification of alkoxysilanes TOSHIBA SILICONE (JP) 1997-02-12 EP claimed
CN-1128277-A Flame-resistant polycarbonate moulding compositions BAYER AG (DE) 1996-08-07 CN claimed
EP-0712901-A2 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1996-05-22 EP claimed
US-5104999-A METHOD OF PURIFICATION OF ALKOXYSILANES TOSHIBA SILICONE CO., LTD. (JP) 1992-04-14 US claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed