Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880637 | 0.99 | C5AR1 (0.43) | AKR1C3AKR1C2C5AR1ITGA4ITGB7 | |
| SCHEMBL3893373 | 0.88 | AKR1C3 (0.43) | AKR1C3AKR1C2C5AR1PTGER1PTGER4 | |
| SCHEMBL3882409 | 0.87 | PTGER1 (0.42) | AKR1C3AKR1C2C5AR1PTGER1PTGER4 | |
| SCHEMBL3884852 | 0.84 | THRA (0.46) | AKR1C3AKR1C2C5AR1PTGDR2PTGER1 | |
| SCHEMBL3882712 | 0.83 | THRA (0.47) | AKR1C3AKR1C2C5AR1PTGDR2PTGER1 | |
| SCHEMBL3883663 | 0.82 | C5AR1 (0.44) | C5AR1ITGA4ITGB7PTGDR2PTGER1 | |
| SCHEMBL3884007 | 0.81 | PTGER1 (0.39) | C5AR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3880639 | 0.81 | C5AR1 (0.45) | C5AR1ITGA4ITGB7PTGDR2PTGER1 | |
| SCHEMBL3890246 | 0.80 | PTGER1 (0.40) | C5AR1PTGER1P2RX3PTGER4PTGER3 | |
| SCHEMBL3884002 | 0.80 | F11 (0.40) | P2RX3XDHMAP4K4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |