Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 12/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891660 | 0.88 | APP (0.36) | CHRNA7ARPIK3CDABL1EGFR | |
| SCHEMBL3889305 | 0.87 | APP (0.38) | CHRNA7ARPIK3CDABL1EGFR | |
| SCHEMBL3482990 | 0.87 | THRA (0.48) | CHRNA7ARPIK3CDABL1EGFR | |
| SCHEMBL3897931 | 0.87 | CHRNA7 (0.36) | CHRNA7FFAR4CCNCCDK8 | |
| SCHEMBL3883666 | 0.85 | CHRNA7 (0.42) | CHRNA7 | |
| SCHEMBL3892394 | 0.85 | AKR1C3 (0.38) | — | |
| SCHEMBL3887928 | 0.84 | CHRNA7 (0.41) | CHRNA7SRC | |
| SCHEMBL3882720 | 0.84 | CHRNA7 (0.39) | CHRNA7ARPIK3CDABL1EGFR | |
| SCHEMBL3897348 | 0.82 | PTGS2 (0.41) | ARABL1MTORTGFBR1 | |
| SCHEMBL3891647 | 0.81 | AR (0.35) | CHRNA7ARCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |