Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 12/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883666 | 0.99 | CHRNA7 (0.42) | CHRNA7MDM2GRM2 | |
| SCHEMBL3888290 | 0.90 | P2RX3 (0.38) | XDHGRM2C5AR1SRCYES1 | |
| SCHEMBL3892392 | 0.89 | P2RX3 (0.36) | XDHGRM2C5AR1SRCYES1 | |
| SCHEMBL3888282 | 0.88 | GRM2 (0.39) | CHRNA7MDM2GRM2 | |
| SCHEMBL3881971 | 0.88 | FFAR4 (0.43) | GRM2SRC | |
| SCHEMBL3893026 | 0.86 | GRM2 (0.40) | CHRNA7MDM2GRM2 | |
| SCHEMBL3882968 | 0.86 | THRA (0.46) | CHRNA7XDHC5AR1 | |
| SCHEMBL3884556 | 0.85 | THRA (0.44) | CHRNA7MDM2 | |
| SCHEMBL3889975 | 0.84 | CHRNA7 (0.38) | CHRNA7SRC | |
| SCHEMBL3881996 | 0.84 | KEAP1 (0.40) | XDHC5AR1SRCYES1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |