SCHEMBL38916

SCHEMBL38916

[CH2]C#CCCCCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3461762 0.97 PTPN7 (0.46)
SCHEMBL313520 0.97 PTPN7 (0.46)
SCHEMBL3281239 0.97 PTPN7 (0.46)
SCHEMBL12541540 0.97 PTPN7 (0.46)
SCHEMBL3248000 0.97 PTPN7 (0.46)
SCHEMBL3281607 0.97 PTPN7 (0.46)
SCHEMBL184032 0.97 PTPN7 (0.46)
SCHEMBL455197 0.97 PTPN7 (0.46)
SCHEMBL1792259 0.97 PTPN7 (0.46)
SCHEMBL12541573 0.97 PTPN7 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023202664-A1 SMALL MOLECULE IL-17A MODULATORS BEIGENE, LTD. (KY) 2023-10-26 WO claimed
EP-2668176-B1 A NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS SPHAERA PHARMA PTE LTD (SG) 2017-05-17 EP claimed
US-9428482-B2 Process for synthesis of polyphenols SPHAERA PHARMA PTE. LTD. (SG) 2016-08-30 US claimed
CN-103467463-B One lignans analog derivative and its production and use 南开大学 2016-06-22 CN claimed
US-20140031421-A1 NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS SPHAERA PHARMA PTE. LTD. (SG) 2014-01-30 US claimed
US-20120232105-A1 PHARMACEUTICAL COMPOSITION FOR INHIBITING OSTEOCLAST GROWTH NATIONAL DEFENSE MEDICAL CENTER (TW) 2012-09-13 US claimed
US-RE39836-E1 Macrolide antinfective agents KOSAN BIOSCIENCES, INC. (US) 2007-09-11 US claimed
EP-1171446-B1 MACROLIDE ANTIINFECTIVE AGENTS KOSAN BIOSCIENCES INC (US) 2006-09-20 EP claimed
US-6794366-B2 ERYTHRONOLIDE DERIVATIVES THAT CONTAIN MODIFICATIONS FROM THE NATIVE STRUCTURE AT POSITIONS 13, E.G., 15-(QUINOL-4-YL-ACETAMIDOERYTHROMYCIN A; BACTERICIDES; PRESERVATIVES KOSAN BIOSCIENCES, INC. 2004-09-21 US claimed
US-20040171616-A9 Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade PHARMACIA CORPORATION 2004-09-02 US claimed
WO-2001068605-A1 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2001-09-20 WO claimed
US-20010018446-A1 Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2001-08-30 US claimed
WO-2001049699-A1 MACROLIDE ANTIINFECTIVE AGENTS KOSAN BIOSCIENCES, INC. (US) 2001-07-12 WO claimed
WO-2000063224-A2 MACROLIDE ANTIINFECTIVE AGENTS KOSAN BIOSCIENCES, INC. (US) 2000-10-26 WO claimed
WO-2000063225-A2 MACROLIDE ANTIINFECTIVE AGENTS KOSAN BIOSCIENCES, INC. (US) 2000-10-26 WO claimed
CN-1044811-C Pyrrolopyridazine derivatives SANKYO CO (JP) 1999-08-25 CN claimed
CN-1143964-A Pyrrolopyridazine derivative SANKYO CO (JP) 1997-02-26 CN claimed
US-5043346-A Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US claimed
EP-0078663-A2 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-11 EP claimed
EP-0063905-A1 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-03 EP claimed