SCHEMBL3891707

SCHEMBL3891707

CCO[SiH](Nc1ccccc1)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.42
GAA P10253 3/20 0.39
TSHR P16473 2/20 0.37
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 4/20 0.35
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 3/20 0.35
CTSD P07339 1/20 0.35
MAPT P10636 5/20 0.34
MAPK1 P28482 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
PTGS2 P35354 1/20 0.33
HTR2B P41595 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4030087 0.81 NPSR1 (0.41) NPSR1GAATSHRHPGDTDP1
SCHEMBL28660896 0.79 ALDH1A1 (0.42) NPSR1GAATSHRHPGDTDP1
SCHEMBL3886650 0.75 TSHR (0.42) TSHRHPGDTDP1ALDH1A1HSD17B10
SCHEMBL304793 0.72 TSHR (0.58) NPSR1GAATSHRHPGDTDP1
SCHEMBL1854492 0.71 MAPT (0.40) NPSR1GAATSHRHPGDALDH1A1
SCHEMBL5598837 0.71 TSHR (0.56) NPSR1GAATSHRHPGDTDP1
SCHEMBL15135157 0.71 MAPT (0.43) GAAHPGDTDP1ALDH1A1HSD17B10
SCHEMBL16794750 0.70 TSHR (0.42) NPSR1GAATSHRHPGDTDP1
SCHEMBL10359188 0.68 TSHR (0.40) NPSR1GAATSHRHPGDTDP1
SCHEMBL774108 0.68 MAPT (0.47) NPSR1GAAALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed