Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | ATM | Q13315 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 5/20 | 0.48 |
| ▸ | CASP7 | P55210 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | GLA | P06280 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953684 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL3901017 | 0.76 | ALDH1A1 (0.71) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL24862103 | 0.72 | ALDH1A1 (0.60) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL16563064 | 0.72 | IGLV6-57 (0.72) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL16563181 | 0.71 | ALDH1A1 (0.51) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL8122108 | 0.70 | ALDH1A1 (0.75) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL16563262 | 0.69 | IGLV6-57 (0.54) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL23704571 | 0.69 | MAOB (0.61) | ALDH1A1ATMMEN1KMT2AHPGD | |
| SCHEMBL21456974 | 0.69 | ALDH1A1 (0.56) | ALDH1A1ATMMEN1KMT2ATDP1 | |
| SCHEMBL14408374 | 0.68 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553869-B2 | Protein probe compounds, compositions, and methods | PIERCE BIOTECHNOLOGY, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080026478-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | PIERCE BIOTECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2008013543-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | PIERCE BIOTECHNOLOGY, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080026478-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | HIRA, CUTA, MRPS27 | ALDH1A1 4053/4885ATM 3334/4885MEN1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.