Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | AQP4 | P55087 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893137 | 0.82 | RAB9A (0.60) | RAB9AKDM4EAQP4SMN1; SMN2NPC1 | |
| SCHEMBL3891438 | 0.80 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1KMT2ALMNA | |
| SCHEMBL3893217 | 0.73 | GAA (0.42) | SMN1; SMN2KMT2ALMNAALDH1A1GAA | |
| SCHEMBL9963857 | 0.73 | KDM4E (0.61) | RAB9AKDM4EAQP4SMN1; SMN2NPC1 | |
| SCHEMBL3891666 | 0.72 | ALOX5 (0.60) | RAB9ASMN1; SMN2NPC1KMT2ALMNA | |
| SCHEMBL12324390 | 0.72 | GAA (0.53) | SMN1; SMN2KMT2ALMNAALDH1A1GAA | |
| SCHEMBL3894403 | 0.72 | SIRT2 (0.48) | SMN1; SMN2LMNAALDH1A1GAATDP1 | |
| SCHEMBL2664674 | 0.72 | RAB9A (0.59) | RAB9AKDM4EAQP4SMN1; SMN2NPC1 | |
| SCHEMBL3379803 | 0.72 | AQP4 (0.70) | RAB9AKDM4EAQP4SMN1; SMN2NPC1 | |
| SCHEMBL3891472 | 0.72 | GLA (0.50) | RAB9AKDM4ENPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | claimed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | claimed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | claimed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | disclosed |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
| WO-2003010143-A1 | DIALKYLHYDROXYBENZOIC ACID DERIVATIVES CONTAINING METAL CHELATING GROUPS AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | RAB9A 764/4885KDM4E 3297/4885AQP4 4062/4885 |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | RAB9A 1174/4885KDM4E 2974/4885AQP4 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.