Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699938 | 0.74 | ALDH1A1 (0.50) | HPGDALDH1A1GFERKMT2AMEN1 | |
| SCHEMBL4649406 | 0.73 | MEN1 (0.50) | HPGDALDH1A1GFERKDM4ETSHR | |
| SCHEMBL10498731 | 0.70 | ALDH1A1 (0.50) | HPGDALDH1A1GFERKMT2AMEN1 | |
| SCHEMBL15493662 | 0.69 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8655031 | 0.69 | KDM4E (0.53) | HPGDALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL3277745 | 0.68 | RAB9A (0.44) | HPGDALDH1A1GFERTSHRKMT2A | |
| SCHEMBL15549217 | 0.67 | ALDH1A1 (0.47) | HPGDALDH1A1GFERKMT2AMEN1 | |
| SCHEMBL211460 | 0.66 | TSHR (0.44) | HPGDALDH1A1GFERTSHRKMT2A | |
| SCHEMBL8087997 | 0.65 | ALDH1A1 (0.70) | HPGDALDH1A1GFERKDM4ETSHR | |
| SCHEMBL3820980 | 0.63 | ALDH1A1 (0.47) | HPGDALDH1A1GFERKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557248-B2 | Method of forming a carbon-heteroatom bond | RHODIA CHIMIE (FR) | 2009-07-07 | — | — | US | disclosed |
| US-20070243999-A1 | Method of Forming a Carbon-Heteroatom Bond | RHODIA CHIMIE (FR) | 2007-10-18 | — | — | US | disclosed |