SCHEMBL4649406

SCHEMBL4649406

c1ccc(C(=NN(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ ALDH1A1 P00352 6/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ HPGD P15428 4/20 0.44
▸ GFER P55789 1/20 0.44
▸ MAPK1 P28482 2/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.41
▸ GAA P10253 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ POLB P06746 2/20 0.36
▸ EIF4H Q15056 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ CTSL P07711 1/20 0.36
▸ CTSK P43235 1/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655031 0.81 KDM4E (0.53) MEN1KMT2AALDH1A1HPGDMAPK1
SCHEMBL21730077 0.81 MAOB (0.44) MEN1KMT2AALDH1A1HPGDGFER
SCHEMBL12402049 0.78 SIGMAR1 (0.44) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL22536007 0.78 KMT2A (0.38) MEN1KMT2AALDH1A1ALOX15HPGD
SCHEMBL11699938 0.77 ALDH1A1 (0.50) MEN1KMT2AALDH1A1HPGDGFER
SCHEMBL21730129 0.76 MEN1 (0.37) MEN1KMT2AALDH1A1HPGDGFER
SCHEMBL3842986 0.76 ALDH1A1 (0.47) MEN1KMT2AALDH1A1ALOX15HPGD
SCHEMBL5671680 0.75 HNF4A (0.38) MEN1KMT2AALDH1A1ALOX15HPGD
SCHEMBL322061 0.74 KMT2A (0.44) MEN1KMT2AALDH1A1ALOX15HPGD
SCHEMBL322060 0.74 KMT2A (0.44) MEN1KMT2AALDH1A1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1668409-A4 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD UNIV CALIFORNIA (US) 2008-08-27 — — EP claimed
EP-1668409-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD The Regents of The University of California (US) 2006-06-14 — — EP claimed
US-6862125-B2 Reversible electro-optic device employing aprotic molten salts and method THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-01 — — US claimed
WO-2004099863-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-11-18 — — WO claimed
US-20040227983-A1 Reversible electro-optic device employing aprotic molten salts and method LOS ALAMOS NATIOMAL SECURITY, LLC 2004-11-18 — — US claimed
US-20040223207-A1 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD LOS ALAMOS NATIONAL SECUIRTY, LLC 2004-11-11 — — US claimed
US-6587251-B2 Color change of mirror EXON SCIENCE, INC. (TW) 2003-07-01 — — US claimed
US-20030063365-A1 Electrochromic solution containing hydrazone compound and device manufactured with same SEAGATE TECHNOLOGY LLC 2003-04-03 — — US claimed
EP-1288275-A2 Electrochromic solution containing a hydrazone compound and device manufactured with same Exon Science Inc. (TW) 2003-03-05 — — EP claimed
EP-1668409-A4 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD UNIV CALIFORNIA (US) 2008-08-27 — — EP disclosed
US-7317106-B2 Reversible electro-optic device employing aprotic molten salts and method LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-01-08 — — US disclosed
EP-1668409-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD The Regents of The University of California (US) 2006-06-14 — — EP disclosed
US-20060012293-A1 Reversible electro-optic device employing aprotic molten salts and method LOS ALAMOS NATIONAL SECURITY, LLC 2006-01-19 — — US disclosed
US-6862125-B2 Reversible electro-optic device employing aprotic molten salts and method THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-01 — — US disclosed
WO-2004099863-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-11-18 — — WO disclosed
US-20040227983-A1 Reversible electro-optic device employing aprotic molten salts and method LOS ALAMOS NATIOMAL SECURITY, LLC 2004-11-18 — — US disclosed
US-20040223207-A1 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD LOS ALAMOS NATIONAL SECUIRTY, LLC 2004-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060012293-A1 Reversible electro-optic device employing aprotic molten salts and method ALDH1A2, OTC, AOC1 MEN1 9/4885KMT2A 1543/4885ALDH1A1 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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