Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893502 | 1.00 | FFAR4 (0.41) | FFAR4FFAR1THRATHRBPTGES | |
| SCHEMBL27627155 | 0.95 | PTGES (0.38) | FFAR4FFAR1THRATHRBPTGES | |
| SCHEMBL3895738 | 0.91 | PTGES (0.38) | FFAR4PTGESENPP2CHRNA7KCNH2 | |
| SCHEMBL3895730 | 0.87 | PTGS2 (0.38) | FFAR4FFAR1PTGESENPP2PPARG | |
| SCHEMBL3882277 | 0.86 | FFAR4 (0.49) | FFAR4FFAR1THRATHRBPTGES | |
| SCHEMBL3882327 | 0.86 | FFAR4 (0.43) | FFAR4FFAR1THRATHRBENPP2 | |
| SCHEMBL3883485 | 0.84 | FFAR4 (0.48) | FFAR4FFAR1ENPP2PPARGPPARD | |
| SCHEMBL27607971 | 0.81 | FFAR4 (0.39) | FFAR4FFAR1THRATHRBENPP2 | |
| SCHEMBL3888001 | 0.80 | THRA (0.46) | FFAR4THRATHRBENPP2 | |
| SCHEMBL3887997 | 0.80 | THRA (0.46) | FFAR4THRATHRBENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |