Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.38 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.38 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.38 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.38 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884652 | 0.91 | PTGER1 (0.45) | PTGS2ENPP2METPLA2G10PLA2G2A | |
| SCHEMBL3884645 | 0.89 | PTGS2 (0.43) | PTGS2ENPP2METPPARGPPARA | |
| SCHEMBL3893365 | 0.89 | PTGS2 (0.40) | PTGS2ENPP2METPPARGPPARA | |
| SCHEMBL3883391 | 0.88 | PTGS2 (0.41) | PTGS2ENPP2PPARGPPARAALOX5 | |
| SCHEMBL3882075 | 0.88 | PTGS2 (0.43) | PTGS2ENPP2PPARGPPARAPLA2G10 | |
| SCHEMBL3884148 | 0.88 | ENPP2 (0.39) | PTGS2ENPP2PPARGPPARAFFAR4 | |
| SCHEMBL3894526 | 0.88 | PPARG (0.47) | PPARGPPARAPLA2G10PLA2G2APTGER1 | |
| SCHEMBL3886809 | 0.87 | PTGS2 (0.42) | PTGS2ENPP2PPARGPPARAPTGES | |
| SCHEMBL3886886 | 0.87 | PTGER1 (0.41) | PTGS2ENPP2METPPARGPPARA | |
| SCHEMBL3884675 | 0.87 | PTGER1 (0.41) | PTGS2ENPP2METPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |