Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882075 | 0.91 | PTGS2 (0.43) | PTGS2PPARAPPARDENPP2ALOX5 | |
| SCHEMBL3886809 | 0.90 | PTGS2 (0.42) | PTGS2PPARAPPARDENPP2ALOX5 | |
| SCHEMBL3894495 | 0.88 | PTGS2 (0.41) | PTGS2PPARAPPARDENPP2ALOX5 | |
| SCHEMBL3882300 | 0.88 | PTGS2 (0.45) | PTGS2PPARAPPARDENPP2ALOX5 | |
| SCHEMBL3888319 | 0.86 | FFAR1 (0.48) | DRD2DRD3PPARG | |
| SCHEMBL3884645 | 0.86 | PTGS2 (0.43) | PTGS2PPARAPPARDENPP2PPARG | |
| SCHEMBL3893365 | 0.86 | PTGS2 (0.40) | PTGS2PPARAENPP2ALOX5PPARG | |
| SCHEMBL3894657 | 0.85 | PPARA (0.46) | PTGS2PPARAPPARDENPP2PPARG | |
| SCHEMBL3888486 | 0.85 | LTB4R (0.41) | PTGS2PPARAPPARDENPP2PPARG | |
| SCHEMBL3884148 | 0.85 | ENPP2 (0.39) | PTGS2PPARAPPARDENPP2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |