SCHEMBL3895585

SCHEMBL3895585

C=C(CC(=O)NC)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TET2 Q6N021 5/20 0.38
MCL1 Q07820 1/20 0.37
LMNA P02545 1/20 0.37
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11668739 0.80 LMNA (0.44) ALOX15HSD17B10TET2MCL1LMNA
SCHEMBL20326590 0.79 MCL1 (0.37) MCL1LMNAALDH1A1
SCHEMBL11436554 0.79 MCL1 (0.37) MCL1LMNAALDH1A1
SCHEMBL5176364 0.77 TDP1 (0.39) MCL1LMNAALDH1A1
SCHEMBL1809603 0.76 ALOX15 (0.57) ALOX15HSD17B10TET2TET3TET1
Itaconate SCHEMBL5875042 0.76 ALOX15 (0.65) ALOX15HSD17B10TET2TET3TET1
Itaconate SCHEMBL5875036 0.76 ALOX15 (0.65) ALOX15HSD17B10TET2TET3TET1
SCHEMBL12147263 0.76 ALOX15 (0.46) ALOX15HSD17B10TET2TET3TET1
SCHEMBL5177523 0.75 MCL1 (0.41) ALOX15HSD17B10TET2MCL1TET3
SCHEMBL20326365 0.75 MCL1 (0.34) MCL1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20190105632-A1 MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF SARTORIUS STEDIM BIOTECH GMBH (DE) 2019-04-11 US disclosed
CN-104125860-B Inorganic/high molecular hybrid catalytic material with high activity in various solvents 日本高度纸工业株式会社 2017-03-08 CN disclosed
US-9527067-B2 Inorganic/polymeric hybrid catalytic materials containing metal nano-particles therein NIPPON KODOSHI CORPORATION (JP) 2016-12-27 US disclosed
CN-105764611-A Catalyst system for continuous flow reactor, method for the production thereof and use thereof 阿尔伯塔大学理事会 2016-07-13 CN disclosed
CN-104125860-A Inorganic/high molecular hybrid catalytic material with high activity in various solvents NIPPON KODOSHI CORP 2014-10-29 CN disclosed
US-20140128251-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN NIPPON KODOSHI CORPORATION (JP) 2014-05-08 US disclosed
EP-2688668-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN Nippon Kodoshi Corporation (JP) 2014-01-29 EP disclosed
WO-2012176341-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN NIPPON KODOSHI CORPORATION (JP) 2012-12-27 WO disclosed
EP-0976722-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2009-03-11 EP disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
EP-0976722-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190105632-A1 MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF NEFM, ADM2, IGFBP4 ALOX15 4510/4885HSD17B10 4765/4885TET2 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.