Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrimidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL21056190 | 1.00 | NAPRT (0.42) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL9322876 | 1.00 | NAPRT (0.42) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL29040951 | 1.00 | NAPRT (0.42) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL27984552 | 0.97 | NAPRT (0.41) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL22711662 | 0.97 | NAPRT (0.41) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL15510413 | 0.89 | NAPRT (0.37) | NAPRTCA5ACA5B | |
| Pyrimidine SCHEMBL2931357 | 0.88 | NAPRT (0.39) | NAPRTTSHRTDP1 | |
| Pyrimidine SCHEMBL11689582 | 0.88 | CA1 (0.47) | NAPRTCA5ACA5BTSHRTDP1 | |
| Pyrimidine SCHEMBL6623921 | 0.88 | NAPRT (0.39) | NAPRTTSHRTDP1 | |
| Pyrimidine SCHEMBL27442310 | 0.88 | NAPRT (0.39) | NAPRTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094372-A | Preparation method and application for regulating perovskite thin film crystallization | — | 2026-05-26 | — | — | CN | claimed |
| US-20260078296-A1 | SUSTAINED-RELEASE SCALE INHIBITORS | Materials Engineering and Technical Support Services (US) | 2026-03-19 | — | — | US | claimed |
| WO-2024059615-A2 | SUSTAINED-RELEASE SCALE INHIBITORS | MATERIALS ENGINEERING AND TECHNICAL SUPPORT SERVICES CORPORATION (US) | 2024-03-21 | — | — | WO | claimed |
| CN-115980205-A | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product | 江苏省食品药品监督检验研究院 | 2023-04-18 | — | — | CN | claimed |
| CN-109535083-A | The preparation method of 2,4,5-triamino-6-hydroxypyrimidine sulfate and folic acid | 浙江本立科技股份有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-106117207-B | A method of preparing guanine | 江苏八巨药业有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108558776-A | The preparation method of 2,4- diamino -5- nitroso -6- hydroxy pyrimidines and guanine | 潍坊奥通药业有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-105541845-B | Folic acid cleanly production technique | 青岛琅琊台集团股份有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-106117207-A | A kind of new method preparing guanine | 江苏八巨药业有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-122094372-A | Preparation method and application for regulating perovskite thin film crystallization | — | 2026-05-26 | — | — | CN | disclosed |
| EP-3166981-B1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | DSM NUTRITIONAL PRODUCTS LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20260078296-A1 | SUSTAINED-RELEASE SCALE INHIBITORS | Materials Engineering and Technical Support Services (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4340807-B1 | HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS | LUBRIZOL ADVANCED MAT INC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-12514267-B2 | Oligosaccharide compositions for use as animal feed and methods of producing thereof | DSM NUTRITIONAL PRODUCTS, LLC (US) | 2026-01-06 | — | — | US | disclosed |
| EP-0508375-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY LTD. (KR) | 1992-10-14 | — | — | EP | disclosed |
| EP-0210227-A1 | PYRIMIDINE SULFATES FOR HAIR GROWTH. | UPJOHN CO (US) | 1987-02-04 | — | — | EP | disclosed |
| WO-1986004231-A1 | PYRIMIDINE SULFATES FOR HAIR GROWTH | THE UPJOHN COMPANY (US) | 1986-07-31 | — | — | WO | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4183934-A | NONALIURETIC DIURETICS | ABBOTT LABORATORIES (US) | 1980-01-15 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078296-A1 | SUSTAINED-RELEASE SCALE INHIBITORS | CEL, TST, CD44 | NAPRT 4075/4885CA5A 3365/4885CA5B 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.