SCHEMBL3896906

SCHEMBL3896906

NC(=S)Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
TYR P14679 1/20 0.52
TAS2R38 P59533 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
ALOX12 P18054 1/20 0.52
CYP2C19 P33261 1/20 0.52
CA2 P00918 2/20 0.49
CA5A P35218 1/20 0.49
KMT2A Q03164 2/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NT5E P21589 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3896251 0.98 ALDH1A1 (0.50) ALDH1A1TSHRTP53TYRTAS2R38
SCHEMBL3835013 0.84 CA2 (0.68) ALDH1A1CA2CA5AKMT2APLK1
SCHEMBL12994191 0.84 TAS2R38 (0.52) ALDH1A1TSHRTAS2R38CYP2C19CA2
SCHEMBL3896252 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTP53TYRTAS2R38
SCHEMBL11245631 0.82 TGM2 (0.54) ALDH1A1TSHRTP53TYRTAS2R38
SCHEMBL3893567 0.82 CA1 (0.59) ALDH1A1TSHRCA2KMT2AGAA
SCHEMBL5366779 0.81 MAPT (0.63) ALDH1A1CA2KMT2AGAAMAPT
SCHEMBL11514497 0.80 TSHR (0.48) ALDH1A1TSHRCA2KMT2ASMN1; SMN2
SCHEMBL3897055 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTP53TYRTAS2R38
SCHEMBL3893212 0.80 CA1 (0.57) ALDH1A1TSHRCA2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US claimed
EP-1113806-B1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA PTY LTD (AU) 2007-09-05 EP claimed
EP-0765357-B9 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-08-16 EP claimed
EP-0927217-B1 ANGIOGENIC INHIBITORY COMPOUNDS STARPHARMA PTY LTD (AU) 2006-05-03 EP claimed
EP-0765357-B8 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-03-08 EP claimed
EP-0765357-B1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 2005-12-14 EP claimed
CN-1163235-C Antiviral linear polymer О 2004-08-25 CN claimed
CN-1161128-C Angiogenic inhibitory compounds О 2004-08-11 CN claimed
EP-1113805-A4 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LTD (AU) 2004-05-19 EP claimed
CN-1134486-C Antiviral dendrimers BIOMOLECULAR RES INST LTD (AU) 2004-01-14 CN claimed
CN-1225653-A Antiviral linear polymer BIOMOLECULAR RES INST LTD (AU) 1999-08-11 CN claimed
CN-1225654-A Angiogenic inhibitory compounds BIOMOLECULAR RES INST LTD (AU) 1999-08-11 CN claimed
EP-0928306-A1 ANTIVIRAL LINEAR POLYMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1999-07-14 EP claimed
EP-0927217-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1999-07-07 EP claimed
WO-1998003573-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1998-01-29 WO claimed
WO-1998003572-A1 ANTIVIRAL LINEAR POLYMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1998-01-29 WO claimed
EP-0765357-A4 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 1997-07-30 EP claimed
CN-1154123-A Antiviral dendrimers BIOMOLECULAR RES INST LTD (AU) 1997-07-09 CN claimed
EP-0765357-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1997-04-02 EP claimed
WO-1995034595-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1995-12-21 WO claimed