Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.51 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425678 | 0.90 | ALDH1A1 (0.55) | KEAP1NFE2L2BCL2BCL2L1MCL1 | |
| SCHEMBL4774366 | 0.88 | PRMT1 (0.50) | KEAP1NFE2L2BCL2BCL2L1MCL1 | |
| SCHEMBL4983596 | 0.87 | HDAC1 (0.63) | BCL2BCL2L1MCL1SLC16A3TSHR | |
| SCHEMBL21647679 | 0.85 | LTB4R (0.51) | KEAP1NFE2L2BCL2BCL2L1MCL1 | |
| SCHEMBL5205026 | 0.84 | ALDH1A1 (0.58) | KEAP1NFE2L2SQSTM1ALDH1A1TSHR | |
| SCHEMBL21647689 | 0.83 | TDP1 (0.47) | KEAP1NFE2L2BCL2BCL2L1MCL1 | |
| SCHEMBL3554985 | 0.83 | TDP1 (0.53) | KEAP1NFE2L2BCL2BCL2L1MCL1 | |
| SCHEMBL3556581 | 0.82 | SLC16A3 (0.58) | MCL1RAB9ASLC16A3ALDH1A1TSHR | |
| SCHEMBL21647713 | 0.81 | FFAR1 (0.60) | KEAP1NFE2L2MCL1NPC1RAB9A | |
| SCHEMBL7376447 | 0.81 | MAPT (0.47) | BCL2BCL2L1MCL1SLC16A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |