Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866143 | 0.90 | LMNA (0.59) | ALDH1A1KDM4EPTGDR2KMT2ATSHR | |
| SCHEMBL16397682 | 0.86 | BCL2 (0.55) | ALDH1A1KDM4EPTGDR2KMT2ATSHR | |
| SCHEMBL398529 | 0.84 | KMT2A (0.47) | ALDH1A1KDM4EPTGDR2KMT2ATSHR | |
| SCHEMBL3897238 | 0.84 | KEAP1 (0.55) | ALDH1A1KDM4EKMT2ATSHRPOLB | |
| SCHEMBL12050285 | 0.83 | RECQL (0.57) | ALDH1A1KDM4EKMT2ATSHRRECQL | |
| SCHEMBL3563417 | 0.82 | PTGDR2 (0.56) | ALDH1A1KDM4EPTGDR2KMT2ATSHR | |
| SCHEMBL7888388 | 0.81 | PTGS2 (0.54) | ALDH1A1KDM4ECXCL8KMT2AKEAP1 | |
| SCHEMBL10272404 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2ATSHRRECQLPOLB | |
| SCHEMBL21647703 | 0.81 | PTGDR2 (0.49) | ALDH1A1KDM4EPTGDR2KMT2ATSHR | |
| SCHEMBL7425678 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ATSHRSQSTM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |