Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578276 | 0.88 | SLC16A3 (0.47) | PRMT1SLC16A3KMT2ATSHRMEN1 | |
| SCHEMBL3897238 | 0.88 | KEAP1 (0.55) | SLC16A3KMT2ATSHRALDH1A1POLB | |
| SCHEMBL4983596 | 0.84 | HDAC1 (0.63) | SLC16A3KMT2ATSHRMEN1BCL2 | |
| SCHEMBL7425678 | 0.81 | ALDH1A1 (0.55) | SLC16A3KMT2ATSHRALDH1A1BCL2 | |
| Methane SCHEMBL7208092 | 0.80 | HTR6 (0.56) | SLC16A3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL3556581 | 0.79 | SLC16A3 (0.58) | SLC16A3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL10438570 | 0.78 | ALDH1A1 (0.57) | SLC16A3KMT2ATSHRALDH1A1POLB | |
| SCHEMBL5205026 | 0.78 | ALDH1A1 (0.58) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL28290008 | 0.78 | ALDH1A1 (0.53) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL12050285 | 0.78 | RECQL (0.57) | KMT2ATSHRMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |