Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839555 | 1.00 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL11651471 | 0.95 | TSHR (0.42) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL29011335 | 0.93 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL6231047 | 0.87 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL18125121 | 0.87 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL16357610 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL362466 | 0.83 | ALOX15 (0.42) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL28925058 | 0.82 | MEN1 (0.44) | TSHRMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL8413866 | 0.82 | MEN1 (0.33) | TSHRMEN1KMT2ACYP3A4ALOX15 | |
| Alcohol SCHEMBL5316638 | 0.81 | ALDH1A1 (0.39) | TSHRALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283553-A1 | POLYETHERS, POLYAMINES, POLYTHIOETHERS, AND METHODS FOR MAKING SAME | P2 SCIENCE, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20170283553-A1 | POLYETHERS, POLYAMINES, POLYTHIOETHERS, AND METHODS FOR MAKING SAME | P2 SCIENCE, INC. | 2017-10-05 | — | — | US | disclosed |
| EP-1931324-B1 | DES-C,D ANALOGS OF 1ALPHA,25-DIHYDROXY-19-NORVITAMIN D3 | WISCONSIN ALUMNI RES FOUND (US) | 2015-01-28 | — | — | EP | disclosed |
| US-7534777-B2 | Des-C,D analogs of 1α,25-dihydroxy-19-norvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1931324-A2 | DES-C,D ANALOGS OF 1ALPHA,25-DIHYDROXY-19-NORVITAMIN D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-06-18 | — | — | EP | disclosed |
| US-20070112077-A1 | Des-C,D analogs of 1alpha,25-dihydroxy-19-norvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-17 | — | — | US | disclosed |
| WO-2007028000-A2 | DES-C,D ANALOGS OF 1ALPHA,25-DIHYDROXY-19-NORVITAMIN D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
| US-4311617-A | Perfumery compositions | BUSH BOAKE ALLEN LIMITED (GB) | 1982-01-19 | — | — | US | disclosed |
| US-4287133-A | AN THE INTERMEDIATE SCHIFF BASE INVOLVED IN PRODUCTION | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4281177-A | FLAVORING OR PERFUMES FOR COSMETICS, DETERGENTS, TOBACCO | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-07-28 | — | — | US | disclosed |
| US-4242281-A | SULFITE ADDITION OF 2,6-DIMETHYL-5-HEPTENAL | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283553-A1 | POLYETHERS, POLYAMINES, POLYTHIOETHERS, AND METHODS FOR MAKING SAME | PARG, PUF60, PARN | TSHR 4232/4885ALDH1A1 3460/4885MEN1 484/4885 |
| US-20070112077-A1 | Des-C,D analogs of 1alpha,25-dihydroxy-19-norvitamin D3 | CYP24A1, VDR, CYP2R1 | TSHR 915/4885ALDH1A1 2059/4885MEN1 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.