SCHEMBL3898609

SCHEMBL3898609

C=C(C)C(=O)O[SiH](CCCC)OC

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.39
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524128 0.89 ALDH1A1 (0.41) TSHRALDH1A1THRB
SCHEMBL12504214 0.74 DGKA (0.38) TSHRALDH1A1
SCHEMBL919874 0.74 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL15535955 0.73 TSHR (0.41) TSHRALDH1A1
SCHEMBL136943 0.73 TSHR (0.55) TSHRALDH1A1THRB
SCHEMBL8677711 0.73 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL3446474 0.73 THRB (0.39) TSHRALDH1A1THRB
SCHEMBL10703811 0.73 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL35127 0.71 TSHR (0.58) TSHRALDH1A1THRB
SCHEMBL4059702 0.71 ALDH1A1 (0.35) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7510775-B2 Composition based on isotactic polypropylene obtained by metallocene catalysis and on grafted isotactic polypropylene obtained by ziegler-natta catalysis ARKEMA FRANCE (FR) 2009-03-31 US disclosed
US-7459214-B2 Binder and a packaging laminate comprising the binder TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) 2008-12-02 US disclosed
EP-1283227-B1 Graft polymer from Isotactic polypropylene obtained with a metallocene catalyst ARKEMA FRANCE (FR) 2007-01-31 EP disclosed
US-7067196-B2 Grafted syndiotactic polypropylene and coextruding binders based on syndiotactic polypropylene ARKEMA (FR) 2006-06-27 US disclosed
US-20060134355-A1 Binder and a packaging laminate comprising the binder TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) 2006-06-22 US disclosed
EP-1599558-B1 A BINDER AND A PACKAGING LAMINATE COMPRISING THE BINDER TETRA LAVAL HOLDINGS & FINANCE (CH) 2006-06-14 EP disclosed
EP-1609593-A2 Packaging material including a silica layer and a polyolefin layer Arkema (FR) 2005-12-28 EP disclosed
EP-1599558-A1 A BINDER AND A PACKAGING LAMINATE COMPRISING THE BINDER TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) 2005-11-30 EP disclosed
CN-1219816-C Isotactic polypropylene and composition with graft isotactic polypropylene as main ingredient ATOFINAS S A (FR) 2005-09-21 CN disclosed
US-20050192406-A1 Composition based on isotactic polypropylene obtained by metallocene catalysis and on grafted isotactic polypropylene obtained by ziegler-natta catalysis ATOFINA S.A. 2005-09-01 US disclosed
EP-1306406-A1 Blend of isotactic metallocene polypropylene and grafted isotactic Ziegler Natta polypropylene Atofina (FR) 2003-05-02 EP disclosed
CN-1403498-A Graft isotaxy polypropylene obtained from metallocene catalysis ATOFINA (FR) 2003-03-19 CN disclosed
US-20030040579-A1 Grafted isotactic polypropylene obtained by metallocene catalysis ATOFINA (FR) 2003-02-27 US disclosed
EP-1283227-A1 Graft polymer from Isotactic polypropylene obtained with a metallocene catalyst Atofina (FR) 2003-02-12 EP disclosed
CN-1079322-C Packaging material comprising a silicon oxide layer and a polyolefin layer ATOCHEM ELF SA (FR) 2002-02-20 CN disclosed
US-5731092-A POLYOLEFIN BINDER GRAFTED WITH UNSATURATED ALKOXYSILANE OR EPOXIDE; BONDING STRENGTH ELF ATOCHEM S.A. (FR) 1998-03-24 US disclosed
CN-1130367-A Packaging material including silica layer and polyolefin layer ATOCHEM ELF SA (FR) 1996-09-04 CN disclosed
EP-0716631-A1 PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER ELF ATOCHEM S.A. (FR) 1996-06-19 EP disclosed
WO-1996000656-A1 PACKAGING MATERIAL INCLUDING A SILICA LAYER AND A POLYOLEFIN LAYER ELF ATOCHEM S.A. (FR) 1996-01-11 WO disclosed
US-4749727-A THREE-DIMENSIONAL CROSSLINKING; EPOXIDES, UNSATURATED ALKOXYSILANES; WATER CURABLE KANSAI PAINT CO., LTD. (JP) 1988-06-07 US disclosed