Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 11/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 10/20 | 0.33 |
| ▸ | DRD2 | P14416 | 9/20 | 0.33 |
| ▸ | DRD3 | P35462 | 9/20 | 0.33 |
| ▸ | HTR2A | P28223 | 9/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909295 | 0.85 | HTR2C (0.45) | HTR6MEN1MAPTKMT2AHTR2C | |
| SCHEMBL3892958 | 0.85 | LMNA (0.44) | HTR6HTR2CDRD2DRD3HTR2A | |
| SCHEMBL14411990 | 0.82 | HTR6 (0.43) | HTR6HTR2CDRD2DRD3HTR2A | |
| SCHEMBL5452773 | 0.82 | USP2 (0.42) | HTR6HTR2CDRD2DRD3HTR2A | |
| SCHEMBL5453002 | 0.82 | USP2 (0.42) | ALDH1A1HTR6GAAKMT2AHTR2C | |
| SCHEMBL5445721 | 0.81 | USP2 (0.41) | HTR6MAPTHTR2CDRD2DRD3 | |
| SCHEMBL5452896 | 0.81 | HTR2C (0.42) | ALDH1A1HTR6HPGDHTR2CDRD2 | |
| SCHEMBL5462456 | 0.81 | USP2 (0.41) | ALDH1A1HTR6MEN1MAPTKMT2A | |
| SCHEMBL3907770 | 0.80 | MAOB (0.52) | ALDH1A1HTR6MAOBHTR2CDRD2 | |
| SCHEMBL5459209 | 0.79 | DRD1 (0.43) | ALDH1A1GAAHTR2CDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504392-B2 | 2,3,4,5-tetrahydro-1H-3-benzazepines and their medical use | GLAXO GROUP LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |
| US-20080269197-A1 | antipsychotic agents; phenylsulfonyl compounds; 7-Methoxy-8-(3-phenoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; schizophrenia | GLAXO GROUP LIMITED | 2008-10-30 | — | — | US | disclosed |
| EP-1511727-B1 | AROMATIC SULFONES AND THEIR MEDICAL USE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |
| US-20050261279-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269197-A1 | antipsychotic agents; phenylsulfonyl compounds; 7-Methoxy-8-(3-phenoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; schizophrenia | SIGMAR1, CBR3, CBR1 | ALDH1A1 2673/4885HTR6 103/4885MAOB 291/4885 |
| US-20050261279-A1 | Compounds | CBR1, CBR3, OXER1 | ALDH1A1 2694/4885HTR6 811/4885MAOB 2012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.