Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452773 | 0.91 | USP2 (0.42) | HTR6USP2SMN1; SMN2HTR2CCYP3A4 | |
| SCHEMBL5453002 | 0.91 | USP2 (0.42) | HTR6USP2SMN1; SMN2HTR2CCYP3A4 | |
| SCHEMBL5455402 | 0.90 | HRH3 (0.38) | HTR6USP2SMN1; SMN2HRH3HTR2C | |
| SCHEMBL5462456 | 0.90 | USP2 (0.41) | HTR6USP2SMN1; SMN2HRH3HTR2C | |
| SCHEMBL5452896 | 0.90 | HTR2C (0.42) | HTR6USP2SMN1; SMN2HTR2CCYP3A4 | |
| SCHEMBL5445721 | 0.90 | USP2 (0.41) | HTR6USP2SMN1; SMN2HTR2CCYP3A4 | |
| SCHEMBL5466786 | 0.89 | SIGMAR1 (0.42) | HTR6USP2SMN1; SMN2HTR2CDRD2 | |
| SCHEMBL5458151 | 0.89 | LTA4H (0.43) | HTR6USP2SMN1; SMN2LTA4HHTR2C | |
| SCHEMBL5457179 | 0.89 | HTR6 (0.38) | HTR6USP2SMN1; SMN2HRH3HTR2C | |
| SCHEMBL5459209 | 0.88 | DRD1 (0.43) | USP2SMN1; SMN2LTA4HHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225276-A1 | 7-Phenylsulfonyl-Tetrahydro-3-Benzazepine Dervatives as Antipsychotic Agents | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225276-A1 | 7-Phenylsulfonyl-Tetrahydro-3-Benzazepine Dervatives as Antipsychotic Agents | HTR4, DRD4, SLC6A3 | HTR6 166/4885USP2 4595/4885SMN1; SMN2 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.