Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706137 | 0.83 | PPARG (0.51) | CTSKCTSSPPARGPPARAGLA | |
| SCHEMBL3900448 | 0.79 | ATM (0.47) | CTSKCTSSPPARGPPARAACACB | |
| SCHEMBL27730329 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARA | |
| SCHEMBL22042132 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARA | |
| SCHEMBL28108976 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARA | |
| SCHEMBL3900446 | 0.77 | PPARG (0.46) | CTSKCTSSPPARGPPARAGLA | |
| SCHEMBL9295212 | 0.75 | CTSK (0.55) | CTSKCTSSPPARGPPARA | |
| SCHEMBL18626097 | 0.73 | CTSK (0.61) | CTSKCTSSPPARGPPARASMN1; SMN2 | |
| SCHEMBL13037410 | 0.73 | CTSK (0.61) | CTSKCTSSPPARGPPARASMN1; SMN2 | |
| SCHEMBL17473110 | 0.72 | THRB (0.60) | ACACBGLAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |