Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974845 | 0.83 | LDHA (0.48) | PPARGPPARASYKITGB3ITGA2B | |
| SCHEMBL7836979 | 0.80 | CTSS (0.54) | SYKATMCTSSCTSKCTSL | |
| SCHEMBL3900448 | 0.79 | ATM (0.47) | PPARGPPARASYKELANEITGB3 | |
| SCHEMBL10188447 | 0.79 | ATM (0.56) | SYKATMCTSSCTSKCTSL | |
| SCHEMBL3900441 | 0.77 | CTSK (0.44) | PPARGPPARAELANEITGB3ITGA2B | |
| SCHEMBL20425275 | 0.77 | SYK (0.53) | PPARGPPARASYKITGB3ITGA2B | |
| SCHEMBL13611681 | 0.76 | ITGA4 (0.46) | PPARGPPARAELANEITGB3ITGA2B | |
| SCHEMBL17592938 | 0.72 | CTSS (0.49) | PPARGPPARASYKCTSSCTSK | |
| SCHEMBL662950 | 0.72 | ITGB3 (0.44) | PPARGPPARASYKITGB3ITGA2B | |
| SCHEMBL1826658 | 0.72 | PPARG (0.44) | PPARGPPARASYKPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |