Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931615 | 0.84 | HTT (0.63) | HTTALDH1A1HIF1AHPGDMEN1 | |
| SCHEMBL5166963 | 0.82 | TRPA1 (0.45) | HTTALDH1A1HPGDAKR1C3AKR1C2 | |
| SCHEMBL9525514 | 0.79 | KDM4E (0.50) | HTTALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL5166899 | 0.78 | TRPA1 (0.44) | HTTALDH1A1HPGDAKR1C3AKR1C2 | |
| 3-Prenyl-4-Hydroxyacetophenone SCHEMBL4120403 | 0.76 | HTT (1.00) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16742132 | 0.74 | ALDH1A1 (0.42) | HTTALDH1A1HIF1AHPGDMEN1 | |
| SCHEMBL6652201 | 0.74 | TSHR (0.54) | HTTALDH1A1PTGESPDE4BTSHR | |
| SCHEMBL1607798 | 0.73 | AKR1C3 (0.64) | HTTALDH1A1HPGDAKR1C3AKR1C2 | |
| SCHEMBL3900395 | 0.73 | PTGDR2 (0.44) | HTTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL26136638 | 0.73 | CYP19A1 (0.44) | HTTALDH1A1HIF1AHPGDAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702907-A | Scratch-resistant self-repairing TPU (thermoplastic polyurethane) hot melt adhesive film and preparation method thereof | 广东汇齐新材料有限公司 | 2022-07-05 | — | — | CN | claimed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | claimed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | claimed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | GNPAT, HOGA1, NQO1 | HTT 571/4885ALDH1A1 10/4885HIF1A 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.