Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526406 | 0.86 | SMN1; SMN2 (0.60) | HTTALDH1A1HIF1APTGDRPTGDR2 | |
| SCHEMBL3544993 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1PTGDRPTGDR2ELANE | |
| SCHEMBL4981784 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APTPN1GAA | |
| SCHEMBL22229873 | 0.84 | KDM4E (0.62) | KDM4EHTTALDH1A1HIF1AMEN1 | |
| SCHEMBL9528336 | 0.82 | MRGPRX4 (0.53) | KDM4EHTTALDH1A1PTGDRPTGDR2 | |
| SCHEMBL29537569 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8484361 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9305217 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8418865 | 0.80 | MEN1 (0.50) | KDM4EALDH1A1PTGDRPTGDR2ELANE | |
| SCHEMBL20466300 | 0.80 | ALDH1A1 (0.42) | KDM4EHTTALDH1A1HIF1APTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |