Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861624 | 0.92 | NFE2L2 (0.48) | NFE2L2TRPA1APPMEN1KMT2A | |
| SCHEMBL6405637 | 0.92 | NFE2L2 (0.48) | NFE2L2TRPA1APPMEN1KMT2A | |
| SCHEMBL6031700 | 0.92 | NFE2L2 (0.48) | NFE2L2TRPA1APPMEN1KMT2A | |
| SCHEMBL27661663 | 0.88 | RELA (0.50) | NFE2L2TRPA1APPTRPM8RELA | |
| SCHEMBL21647821 | 0.88 | RELA (0.50) | NFE2L2TRPA1APPTRPM8RELA | |
| SCHEMBL28181696 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TDP1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL22711285 | 0.88 | RELA (0.50) | NFE2L2TRPA1APPTRPM8RELA | |
| SCHEMBL24631161 | 0.87 | ALDH1A1 (0.34) | ALDH1A1TDP1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL27619456 | 0.84 | KDM4E (0.32) | ALDH1A1TDP1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL14196523 | 0.84 | NFE2L2 (0.42) | ALDH1A1TDP1L3MBTL1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150359884-A1 | MULTI-PHOTON ISOMERISATION OF COMBRETASTATINS AND THEIR USE IN THERAPY | BISBY ROGER H (GB) | 2015-12-17 | — | — | US | disclosed |
| EP-1297021-B1 | MULTIPHOTON PHOTOSENSITIZATION SYSTEM | 3M INNOVATIVE PROPERTIES CO (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7091255-B2 | Multiphoton photosensitization system | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050054744-A1 | Multiphoton photosensitization system | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-10 | — | — | US | disclosed |
| US-6852766-B1 | Multiphoton photosensitization system | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1297021-A2 | MULTIPHOTON PHOTOSENSITIZATION SYSTEM | 3M Innovative Properties Company (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001096409-A2 | MULTIPHOTON PHOTOSENSITIZATION SYSTEM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150359884-A1 | MULTI-PHOTON ISOMERISATION OF COMBRETASTATINS AND THEIR USE IN THERAPY | SLC5A6, FLT4, FOLR2 | ALDH1A1 2119/4885TDP1 1416/4885L3MBTL1 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.