Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | Q9HBH1 | 2/20 | 0.35 | |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899691 | 0.85 | CA1 (0.41) | CA1CA2 | |
| SCHEMBL3895879 | 0.85 | SLC1A3 (0.36) | SLC1A3SLC1A2PDF | |
| SCHEMBL3900173 | 0.82 | CA1 (0.56) | PDFCA1CA2 | |
| SCHEMBL3902711 | 0.81 | CA2 (0.50) | SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL3900866 | 0.81 | CA2 (0.50) | SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL6941909 | 0.80 | ALOX5 (0.32) | — | |
| SCHEMBL4269388 | 0.77 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL3901111 | 0.76 | PDF (0.31) | ||
| SCHEMBL3898297 | 0.75 | PDF (0.32) | ||
| SCHEMBL3901129 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | claimed |
| US-7375120-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-20 | — | — | US | claimed |
| EP-1615629-A4 | PEPTIDE DEFORMYLASE INHIBITORS | CHRISTENSEN SIEGFRIED B IV (US) | 2007-02-28 | — | — | EP | claimed |
| US-20060229341-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2006-10-12 | — | — | US | claimed |
| EP-1615629-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Christensen, Siegfried B. IV (US) | 2006-01-18 | — | — | EP | claimed |
| WO-2004098584-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-11-18 | — | — | WO | claimed |
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7375120-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-20 | — | — | US | disclosed |
| US-20060229341-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229341-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | SLC1A3 3318/4885SLC1A2 4306/4885SLC1A1 3802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.