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Lithium Ion

Lithium Ion

SCHEMBL3901626

Cc1cc(C)cc([Al-](c2cc(C)cc(C)c2)(c2cc(C)cc(C)c2)c2cc(C)cc(C)c2)c1.Cc1ccc([Al-](c2ccc(C)cc2C)(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1.[Li+].[Li+].[LiH]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ RAPGEF4 Q8WZA2 3/20 0.33
▸ ACHE P22303 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899907 0.94 TDP1 (0.35) TDP1TP53RAPGEF4ACHECYP3A4
Lithium Ion SCHEMBL136411 0.85 TDP1 (0.44) TDP1TP53RAPGEF4ACHECYP3A4
SCHEMBL1450871 0.83 TDP1 (0.46) TDP1TP53RAPGEF4ACHECYP3A4
Potassium Ion SCHEMBL134597 0.81 TDP1 (0.44) TDP1TP53RAPGEF4ACHECYP3A4
SCHEMBL132865 0.81 TDP1 (0.44) TDP1TP53RAPGEF4ACHECYP3A4
Lithium Ion SCHEMBL135924 0.76 ALDH1A1 (0.42) TDP1RAPGEF4ACHECYP3A4TSHR
SCHEMBL1451703 0.73 ALDH1A1 (0.44) TDP1RAPGEF4ACHECYP3A4TSHR
Potassium Ion SCHEMBL134936 0.71 ALDH1A1 (0.42) TDP1RAPGEF4ACHECYP3A4TSHR
SCHEMBL137999 0.71 ALDH1A1 (0.42) TDP1RAPGEF4ACHECYP3A4TSHR
SCHEMBL538774 0.69 TDP1 (0.34) TDP1TP53ACHECYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773899-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO (US) 2009-02-11 — — EP claimed