SCHEMBL390238

SCHEMBL390238

C=C(C)C(=O)OC1(C(C)(C)CC)CCCCCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
TSHR P16473 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23520529 1.00 THRB (0.33) THRBALDH1A1ADORA3TSHR
SCHEMBL21173122 0.98 ALDH1A1 (0.33) THRBALDH1A1ADORA3TSHR
SCHEMBL21911838 0.87 THRB (0.33) THRBALDH1A1ADORA3TSHR
SCHEMBL354732 0.85 ALDH1A1 (0.33) THRBALDH1A1ADORA3TSHR
SCHEMBL23352251 0.85 ALDH1A1 (0.33) THRBALDH1A1ADORA3TSHR
SCHEMBL1471662 0.84 ADORA3 (0.34) ADORA3
SCHEMBL23563321 0.84 THRB (0.31) THRBALDH1A1TSHR
SCHEMBL21911839 0.83 ALDH1A1 (0.34) THRBALDH1A1TSHR
SCHEMBL263136 0.82 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL12521232 0.82 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2597113-A1 Coating solutions comprising segmented reactive block copolymers BAUSCH & LOMB INCORPORATED (US) 2013-05-29 EP disclosed
US-8377464-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2013-02-19 US disclosed
US-20120157565-A1 Polymerizable Surfactants and Their Use as Device Forming Comonomers BAUSCH HEALTH US, LLC 2012-06-21 US disclosed
US-8197841-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2012-06-12 US disclosed
US-8100528-B2 Coating solutions comprising segmented interactive block copolymers BAUSCH & LOMB INCORPORATED (US) 2012-01-24 US disclosed
US-7942929-B2 Coating solutions comprising segmented reactive block copolymers BAUSCH & LOMB INCORPORATED (US) 2011-05-17 US disclosed
EP-1828813-B1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB (US) 2010-02-10 EP disclosed
US-20090171027-A1 SEGMENTED INTERACTIVE BLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED 2009-07-02 US disclosed
US-20090171049-A1 SEGMENTED REACTIVE BLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED 2009-07-02 US disclosed
US-20090171050-A1 SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED 2009-07-02 US disclosed
EP-0338656-B1 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB (US) 1994-03-02 EP disclosed
EP-0328340-B1 HYDROPHILIC OXYGEN PERMEABLE POLYMERS BAUSCH & LOMB INCORPORATED (US) 1993-03-31 EP disclosed
US-4910277-A Blend of polysiloxane and an interior wetting agent BAUSCH & LOMB INCORPORATED 1990-03-20 US disclosed
EP-0338656-A2 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB INCORPORATED (US) 1989-10-25 EP disclosed
EP-0328340-A2 Hydrophilic oxygen permeable polymers BAUSCH & LOMB INCORPORATED (US) 1989-08-16 EP disclosed
EP-0124017-B1 POLYSILOXANE COMPOSITION WITH IMPROVED SURFACE WETTING CHARACTERISTICS AND BIOMEDICAL DEVICES MADE THEREOF BAUSCH & LOMB INCORPORATED (US) 1989-07-26 EP disclosed
US-4810764-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1989-03-07 US disclosed
US-4652622-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1987-03-24 US disclosed
US-4495361-A N-ALKENOYL TRIALKYSILYL AMINATE BAUSCH & LOMB INCORPORATED (US) 1985-01-22 US disclosed
EP-0124017-A2 Polysiloxane composition with improved surface wetting characteristics and biomedical devices made thereof BAUSCH & LOMB INCORPORATED (US) 1984-11-07 EP disclosed