Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.49 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239423 | 0.81 | JAK2 (0.49) | TYK2CSNK1DCLK2CSNK1A1CSNK1G1 | |
| SCHEMBL27786052 | 0.80 | CYP46A1 (0.44) | TYK2CYP46A1L3MBTL1NPC1RAB9A | |
| SCHEMBL11155208 | 0.79 | MAPT (0.48) | TYK2CYP46A1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6608502 | 0.79 | JAK2 (0.52) | RAB9AFABP4ALDH1A1KDM4ECDC7 | |
| SCHEMBL3902060 | 0.78 | BRD4 (0.44) | MYCFABP4ALDH1A1KDM4ECHEK2 | |
| SCHEMBL6953781 | 0.78 | FABP4 (0.45) | TYK2L3MBTL1NPC1FABP4ALDH1A1 | |
| SCHEMBL1395221 | 0.76 | ALDH1A1 (0.46) | TYK2CYP46A1L3MBTL1CSNK1DCLK2 | |
| SCHEMBL16144183 | 0.75 | ALDH1A1 (0.47) | L3MBTL1NPC1RAB9AMYCMAPK1 | |
| SCHEMBL3646839 | 0.74 | PLK4 (0.54) | CSNK1DCLK2CDC7SIRT3TDP1 | |
| SCHEMBL3907815 | 0.73 | TRPM8 (0.43) | MYCFABP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |