Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907119 | 0.80 | L3MBTL1 (0.53) | NPC1RAB9AKDM6BKDM4CMEN1 | |
| SCHEMBL7824620 | 0.78 | PBRM1 (0.55) | PBRM1FABP3FABP4PLK1MEN1 | |
| SCHEMBL3904040 | 0.76 | L3MBTL1 (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL28762492 | 0.76 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2AMAPT | |
| Enfenamic Acid SCHEMBL25191 | 0.76 | KDM6B (0.68) | NPC1RAB9APLK1KDM6BKDM4C | |
| SCHEMBL6537375 | 0.74 | CCNC (0.48) | RAB9AMEN1KMT2AKDM4EMAPT | |
| Enfenamic Acid SCHEMBL10935569 | 0.74 | KDM6B (0.66) | NPC1RAB9APLK1KDM6BKDM4C | |
| SCHEMBL28655011 | 0.74 | KDM6B (0.57) | NPC1RAB9APLK1KDM6BKDM4C | |
| SCHEMBL3654056 | 0.74 | EGFR (0.60) | RAB9AKDM6BKDM4CMEN1KMT2A | |
| SCHEMBL27691514 | 0.73 | TAAR1 (0.58) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |