Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 3/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908257 | 0.89 | GNRHR (0.40) | GNRHRACHESCN8ATAAR1ALDH1A1 | |
| SCHEMBL3904582 | 0.80 | TAAR1 (0.52) | ACHETAAR1MAPTSMN1; SMN2 | |
| SCHEMBL3916693 | 0.79 | S1PR2 (0.38) | CTSATAAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6462646 | 0.79 | CTSS (0.43) | ACHECTSLCTSSCTSKTAAR1 | |
| SCHEMBL5050611 | 0.77 | MYC (0.44) | SCN8ATAAR1ALDH1A1MYCCA1 | |
| SCHEMBL6927858 | 0.77 | MPO (0.35) | ACHESCN8ATAAR1ALDH1A1TSHR | |
| SCHEMBL1807270 | 0.76 | CES2 (0.39) | CTSLCTSSCTSKTAAR1ALDH1A1 | |
| SCHEMBL1980395 | 0.75 | CES2 (0.38) | CTSLCTSSCTSKTAAR1RIPK1 | |
| SCHEMBL6927900 | 0.73 | SMN1; SMN2 (0.39) | ACHESCN8ATAAR1ALDH1A1NPC1 | |
| SCHEMBL3907818 | 0.73 | AR (0.41) | ACHETAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |