Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908257 | 0.84 | GNRHR (0.40) | MAPTSMN1; SMN2ALDH1A1GAATAAR1 | |
| SCHEMBL3907788 | 0.81 | TAAR1 (0.49) | S1PR2S1PR4MAPK14SLC9A1KMT2A | |
| SCHEMBL3905360 | 0.79 | GNRHR (0.34) | CTSAMAPTSMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL3907818 | 0.79 | AR (0.41) | ARALDH1A1GAATAAR1 | |
| SCHEMBL5050611 | 0.72 | MYC (0.44) | ALDH1A1TAAR1 | |
| SCHEMBL3907470 | 0.71 | GABRG2 (0.36) | MEN1KMT2A | |
| SCHEMBL3907196 | 0.71 | S1PR2 (0.39) | S1PR2S1PR4CTSAMAPTSMN1; SMN2 | |
| SCHEMBL2562083 | 0.71 | P2RX7 (0.38) | MEN1KMT2AMAPTSMN1; SMN2P2RX7 | |
| SCHEMBL2556847 | 0.71 | SLC6A4 (0.36) | MEN1KMT2AP2RX7ALDH1A1 | |
| SCHEMBL6927858 | 0.71 | MPO (0.35) | KMT2AALDH1A1GAATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |