Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5111875 | 0.93 | KDM4E (0.46) | KDM4ELMNASLC6A4SLC6A3TSHR | |
| SCHEMBL15627214 | 0.84 | LMNA (0.47) | KDM4ELMNASLC6A4SLC6A3SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5112469 | 0.82 | CHIT1 (0.41) | LMNASMN1; SMN2HTTNPSR1CYP3A4 | |
| SCHEMBL5111878 | 0.80 | SLC6A4 (0.41) | KDM4ELMNASLC6A4SLC6A3TSHR | |
| Trifluoroacetic Acid SCHEMBL5107141 | 0.79 | HTT (0.41) | KDM4ELMNASMN1; SMN2HTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5106740 | 0.78 | CHRNA7 (0.42) | KDM4ELMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL27563513 | 0.77 | TSHR (0.45) | KDM4ELMNASLC6A4SLC6A3TSHR | |
| SCHEMBL4333871 | 0.76 | POLB (0.60) | LMNAHTTCYP3A4CYP2C9POLB | |
| SCHEMBL5112406 | 0.75 | S1PR4 (0.53) | LMNAHTTNPSR1S1PR2S1PR4 | |
| Trifluoroacetic Acid SCHEMBL5103332 | 0.75 | CHRNA7 (0.47) | LMNASMN1; SMN2HTTNPSR1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711183-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-04-01 | — | — | EP | disclosed |
| EP-1711183-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005067537-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |