Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5111875 | 0.90 | KDM4E (0.46) | CHIT1S1PR4SMN1; SMN2LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5100344 | 0.86 | S1PR4 (0.46) | CHIT1KMT2AS1PR4SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5106740 | 0.84 | CHRNA7 (0.42) | CHIT1S1PR4SMN1; SMN2LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5107141 | 0.82 | HTT (0.41) | CHIT1KMT2AS1PR4SMN1; SMN2LMNA | |
| SCHEMBL3907243 | 0.82 | KDM4E (0.51) | KMT2AS1PR4SMN1; SMN2LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5106657 | 0.81 | S1PR4 (0.47) | CHIT1S1PR4PDK1PDK2PDK3 | |
| SCHEMBL5112474 | 0.81 | NLRP3 (0.37) | KMT2AS1PR4SMN1; SMN2LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5103332 | 0.81 | CHRNA7 (0.47) | SMN1; SMN2LMNAHTTNPSR1PDK1 | |
| Trifluoroacetic Acid SCHEMBL5111906 | 0.80 | RAB9A (0.41) | CHIT1KMT2AS1PR4SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5103243 | 0.74 | AKR1C3 (0.44) | KMT2ASMN1; SMN2LMNAHTTPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | CHIT1 3534/4885KMT2A 2510/4885S1PR4 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.