Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907243 | 0.93 | KDM4E (0.51) | KDM4ELMNASMN1; SMN2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL5112469 | 0.90 | CHIT1 (0.41) | CHIT1LMNASMN1; SMN2HTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5107141 | 0.86 | HTT (0.41) | KDM4ECHIT1LMNASMN1; SMN2HTT | |
| Trifluoroacetic Acid SCHEMBL5106740 | 0.85 | CHRNA7 (0.42) | KDM4ECHIT1LMNASMN1; SMN2HTT | |
| Trifluoroacetic Acid SCHEMBL5103332 | 0.82 | CHRNA7 (0.47) | LMNASMN1; SMN2HTTNPSR1CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL5100344 | 0.82 | S1PR4 (0.46) | CHIT1LMNASMN1; SMN2HTTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5111906 | 0.82 | RAB9A (0.41) | KDM4ECHIT1LMNASMN1; SMN2HTT | |
| SCHEMBL5111878 | 0.82 | SLC6A4 (0.41) | KDM4ELMNASMN1; SMN2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL5106657 | 0.80 | S1PR4 (0.47) | CHIT1S1PR2S1PR4PDK1PDK2 | |
| SCHEMBL15627214 | 0.78 | LMNA (0.47) | KDM4ELMNASMN1; SMN2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | KDM4E 3835/4885CHIT1 3534/4885LMNA 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.