Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588443 | 0.76 | GSK3B (0.50) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL2864455 | 0.73 | — | — | |
| SCHEMBL2420711 | 0.72 | LRRK2 (0.90) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL366728 | 0.72 | — | — | |
| SCHEMBL1618358 | 0.70 | MAOA (0.42) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL17950746 | 0.70 | CSNK1G1 (0.46) | ACVR1LRRK2MAOAMAOBTNKS2 | |
| SCHEMBL17950676 | 0.70 | ROS1 (0.53) | ACVR1LRRK2MAOAMAOBALDH1A1 | |
| SCHEMBL17950748 | 0.70 | CES1 (0.53) | LTKCDK8ACVR1LRRK2DYRK1B | |
| SCHEMBL1368292 | 0.68 | LRRK2 (1.00) | PDGFRAFERLTKCDK8ACVR1 | |
| Hydrochloric Acid SCHEMBL6299954 | 0.67 | LRRK2 (0.95) | PDGFRAFERLTKCDK8ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888234-B1 | HAPTENS OF ARIPIPRAZOLE AND THEIR USE IN IMMUNOASSAYS | JANSSEN PHARMACEUTICA NV (BE) | 2017-12-06 | — | — | EP | disclosed |
| EP-2707361-B1 | FUSED HETEROCYCLIC COMPOUNDS AS SODIUM CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016116058-A1 | TRIAZINE HETEROCYCLIC COMPOUND WITH NEMATICIDAL ACTIVITY AND PREPARATION METHOD THEREFOR AND USAGE THEREOF | 华东理工大学 | 2016-07-28 | — | — | WO | disclosed |
| EP-1817325-B1 | SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS | UNIV LEHIGH (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20070232576-A1 | Sulfated molecular umbrellas as anti-HIV and anti-HSV agents | LEHIGH UNIVERSITY (US) | 2007-10-04 | — | — | US | disclosed |
| EP-1817325-A2 | SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS | Lehigh University (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006034369-A2 | SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS | LEHIGH UNIVERSITY (US) | 2006-03-30 | — | — | WO | disclosed |
| EP-0804231-B1 | SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF | FINN OLIVERA J (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1012285-A1 | BETA-DEFENSINS | ZymoGenetics, Inc. (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0804231-A4 | SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF | FINN OLIVERA J (US) | 1999-08-18 | — | — | EP | disclosed |
| WO-1999013080-A1 | BETA-DEFENSINS | ZYMOGENETICS, INC. (US) | 1999-03-18 | — | — | WO | disclosed |
| EP-0885224-A1 | PROCESS FOR PREPARING GANCICLOVIR DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-23 | — | — | EP | disclosed |
| EP-0804231-A1 | SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF | Finn, Olivera J. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997027195-A9 | PROCESS FOR PREPARING PURINE DERIVATIVES | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997027194-A1 | PROCESS FOR PREPARING PURINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-31 | — | — | WO | disclosed |
| WO-1997027197-A1 | PROCESS FOR PREPARING GANCICLOVIR DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-31 | — | — | WO | disclosed |
| WO-1995003825-A1 | SYNTHETIC MULTIPLE TANDEM REPEAT MUCIN AND MUCIN-LIKE PEPTIDES, AND USES THEREOF | FINN OLIVERA J (US) | 1995-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232576-A1 | Sulfated molecular umbrellas as anti-HIV and anti-HSV agents | RPL17, SSU72, RPL27A | PDGFRA 3791/4885FER 4856/4885LTK 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.