⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420711 | 1.00 | LRRK2 (0.90) | — | |
| SCHEMBL1368292 | 0.95 | LRRK2 (1.00) | — | |
| Hydrochloric Acid SCHEMBL6299954 | 0.93 | LRRK2 (0.95) | — | |
| SCHEMBL28886187 | 0.91 | LRRK2 (0.75) | — | |
| SCHEMBL28740919 | 0.89 | LRRK2 (0.72) | — | |
| SCHEMBL11485594 | 0.85 | LRRK2 (0.73) | — | |
| Isatin SCHEMBL34016 | 0.84 | MAOA (1.00) | — | |
| Isoindigo SCHEMBL12386233 | 0.84 | LRRK2 (0.67) | — | |
| Isatin SCHEMBL973760 | 0.84 | MAOA (1.00) | — | |
| Isoindigo SCHEMBL9899736 | 0.84 | LRRK2 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109055-B | Difunctional compound for EGFR degradation and application thereof | 北京康辰药业股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-112500349-B | Synthesis method of benzolactam compound | 西北师范大学 | 2023-08-22 | — | — | CN | claimed |
| EP-4189067-A2 | DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS | Vertex Pharmaceuticals Incorporated (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116234819-A | Differentiation of pancreatic endocrine cells | 沃泰克斯药物股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-20230063427-A1 | PREPARATION OF CONSERVED HOMOLOGY 1 DOMAINS COMPLEXED TO LIGANDS | IGUMENOVA TATYANA I (US) | 2023-03-02 | — | — | US | claimed |
| CN-115190895-A | High heat polycarbonate copolymer formulations | 高新特殊工程塑料全球技术有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115109055-A | Bifunctional compound for EGFR degradation and application thereof | 北京康辰药业股份有限公司 | 2022-09-27 | — | — | CN | claimed |
| WO-2022026932-A2 | DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-02-03 | — | — | WO | claimed |
| CN-112500349-A | Synthetic method of benzo lactam compound | 西北师范大学 | 2021-03-16 | — | — | CN | claimed |
| US-20180256537-A1 | METHODS FOR SURVIVAL AND REJUVENATION OF DERMAL FIBROBLASTS USING PKC ACTIVATORS | KHAN TAPAN K (US) | 2018-09-13 | — | — | US | claimed |
| EP-0671911-A1 | CARBOXY-PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS | MERCK & CO. INC. (US) | 1995-09-20 | — | — | EP | claimed |
| EP-0623143-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1994-11-09 | — | — | EP | claimed |
| WO-1994012169-A1 | CARBOXY-PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | claimed |
| EP-0586537-A1 | SUBSTITUTED N-CARBOXYALKYLPEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS | MERCK & CO. INC. (US) | 1994-03-16 | — | — | EP | claimed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | claimed |
| EP-0355598-B1 | BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES | BAYER AG (DE) | 1993-06-16 | — | — | EP | claimed |
| WO-1992021360-A1 | SUBSTITUTED N-CARBOXYALKYLPEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS | MERCK & CO., INC. (US) | 1992-12-10 | — | — | WO | claimed |
| US-5126481-A | Cyclization, reduction, decyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | claimed |
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | claimed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | claimed |