Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915600 | 0.83 | MEN1 (0.45) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL3904575 | 0.79 | MEN1 (0.44) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL3916722 | 0.78 | QPCT (0.53) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL3907788 | 0.73 | TAAR1 (0.49) | KMT2AS1PR2S1PR4MAPTSMN1; SMN2 | |
| SCHEMBL3085200 | 0.71 | MAPT (0.46) | MEN1KMT2AMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL880841 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL1643707 | 0.70 | CYP3A4 (0.60) | MEN1KMT2AMAPTCYP3A4TSHR | |
| SCHEMBL3916693 | 0.70 | S1PR2 (0.38) | MEN1KMT2AS1PR2S1PR4MAPT | |
| SCHEMBL5214473 | 0.69 | SMN1; SMN2 (0.39) | MAPTSMN1; SMN2CYP3A4TSHRRECQL | |
| SCHEMBL5579052 | 0.69 | CHRM3 (0.43) | MEN1USP2CASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |