Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214473 | 0.87 | SMN1; SMN2 (0.39) | CHRM3PKMMAPTSMN1; SMN2IDO1 | |
| SCHEMBL3903024 | 0.84 | PSIP1 (0.43) | CHRM3MAPTSMN1; SMN2IDO1MEN1 | |
| SCHEMBL5579139 | 0.84 | HSD11B1 (0.40) | CHRM3MAPTSMN1; SMN2IDO1MEN1 | |
| SCHEMBL1168220 | 0.80 | IDO1 (0.52) | PKMMAPTSMN1; SMN2IDO1MEN1 | |
| SCHEMBL3904434 | 0.77 | QPCT (0.49) | CHRM3MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3906106 | 0.77 | QPCT (0.52) | CHRM3MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL26075333 | 0.76 | DHODH (0.41) | MEN1KMT2A | |
| SCHEMBL1116575 | 0.76 | PKM (0.47) | PKMMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20989248 | 0.73 | NFE2L2 (0.48) | GPR3ALDH1A1NPC1MAPK14 | |
| SCHEMBL23590338 | 0.73 | DHODH (0.58) | MEN1KMT2AALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784391-A1 | PHENANTHRIDINE CARBONYL PHENOLS AS CYTOKINE EXPRESSION MODULATORS | Wyeth (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006028875-A1 | PHENANTHRIDINE CARBONYL PHENOLS AS CYTOKINE MODULATORS | WYETH (US) | 2006-03-16 | — | — | WO | disclosed |