Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901144 | 0.88 | BMP1 (0.47) | ADAMTS4MMP2MMP9MMP13MMP1 | |
| SCHEMBL3911104 | 0.85 | BMP1 (0.56) | MMP2MMP9MMP8MMP14MMP12 | |
| SCHEMBL3901137 | 0.85 | LARS1 (0.51) | LARS1 | |
| SCHEMBL3900011 | 0.79 | BMP1 (0.45) | LARS1ADAMTS4MMP2MMP9MMP12 | |
| SCHEMBL3898472 | 0.78 | BMP1 (0.51) | LARS1 | |
| SCHEMBL3900004 | 0.77 | BMP1 (0.55) | LARS1MMP12 | |
| SCHEMBL3902592 | 0.77 | MMP3 (0.42) | LARS1MMP2MMP9MMP3MMP13 | |
| SCHEMBL28717212 | 0.77 | LARS1 (0.84) | LARS1ADAMTS4MMP2MMP9MMP3 | |
| SCHEMBL18019130 | 0.77 | LARS1 (0.84) | LARS1ADAMTS4MMP2MMP9MMP3 | |
| SCHEMBL3900001 | 0.77 | ALDH1A1 (0.47) | LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | claimed |