Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394462 | 0.78 | ALDH1A1 (0.54) | BACE1PDE4BALDH1A1CYP4A11RAB9A | |
| SCHEMBL18459371 | 0.73 | NUDT1 (0.43) | BACE1NUDT1OPRL1S1PR1 | |
| SCHEMBL395712 | 0.73 | CYP4A11 (0.42) | BACE1PDE4BALDH1A1CYP4A11MEN1 | |
| SCHEMBL10088541 | 0.72 | NUDT1 (0.41) | BACE1NUDT1OPRL1S1PR1 | |
| SCHEMBL2911579 | 0.70 | TNKS2 (0.42) | BACE1NUDT1MEN1KMT2AS1PR1 | |
| SCHEMBL2909089 | 0.70 | BACE1 (0.70) | BACE1NUDT1ALDH1A1THRBALOX15 | |
| SCHEMBL27623711 | 0.69 | NUDT1 (0.49) | BACE1NUDT1MEN1KMT2AS1PR1 | |
| SCHEMBL6567763 | 0.69 | TNKS2 (0.47) | BACE1NUDT1EPHX1MEN1KMT2A | |
| SCHEMBL6567794 | 0.68 | TNKS2 (0.42) | BACE1NUDT1ALDH1A1RECQL | |
| SCHEMBL11837714 | 0.66 | PTGDR2 (0.40) | BACE1NUDT1S1PR1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101327-B2 | Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent | XEROX CORPORATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-20080057424-A1 | Overcoat for electrophotographic imaging member and methods of making and using same | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |