Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919619 | 0.85 | HPGD (0.48) | ALDH1A1POLBMAPTCYP3A4NPC1 | |
| SCHEMBL395712 | 0.84 | CYP4A11 (0.42) | ALDH1A1BACE1CYP4A11MAPTL3MBTL1 | |
| SCHEMBL80684 | 0.80 | ALDH1A1 (0.47) | ALDH1A1BACE1CYP4A11MAPTCYP3A4 | |
| SCHEMBL7761596 | 0.79 | EPHX2 (0.49) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL25445848 | 0.78 | MAPT (0.43) | ALDH1A1POLBMAPTRECQLNPC1 | |
| SCHEMBL390903 | 0.78 | BACE1 (0.36) | ALDH1A1BACE1CYP4A11CYP3A4THRB | |
| SCHEMBL4883797 | 0.78 | FFAR1 (0.54) | ALDH1A1POLB | |
| SCHEMBL1921405 | 0.78 | GAA (0.52) | ALDH1A1POLBMAPTCYP3A4THRB | |
| SCHEMBL1155655 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTCYP3A4THRB | |
| SCHEMBL31549984 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTCYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101327-B2 | Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent | XEROX CORPORATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-20080057424-A1 | Overcoat for electrophotographic imaging member and methods of making and using same | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |