Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452243 | 0.88 | GABRA1 (0.57) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL17047941 | 0.87 | HMGB1 (0.46) | ALDH1A1TSHRHMGB1IAPPALOX5 | |
| SCHEMBL28499133 | 0.85 | HMGB1 (0.45) | ALDH1A1TSHRHMGB1IAPPALOX5 | |
| SCHEMBL27897798 | 0.85 | TSHR (0.58) | ALDH1A1TSHRHSD17B10HMGB1GAA | |
| SCHEMBL1629682 | 0.84 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL9755152 | 0.84 | LMNA (0.53) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL29875722 | 0.84 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL28147567 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10HMGB1 | |
| SCHEMBL6476062 | 0.83 | KDM4E (0.52) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL7954154 | 0.83 | HMGB1 (0.43) | ALDH1A1LMNAHSD17B10HMGB1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736925-A | Circular mRNA vaccine development platform for cancer caused by virus infection | 奥明(杭州)生物医药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112272697-A | Novel lactobacillus fermentum LM1016 strain and composition for preventing or treating cardiovascular disease comprising the same | 韩国亿诺生物有限公司 | 2021-01-26 | — | — | CN | disclosed |
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |
| CN-1622994-A | TGF-beta specific covalently closed antisense molecules | WELGENE PHARMACEUTICALS INC (KR) | 2005-06-01 | — | — | CN | disclosed |
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |