Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919321 | 0.89 | SHMT1 (0.36) | FFAR4SHMT1SHMT2MAPTHPGD | |
| SCHEMBL987167 | 0.83 | MEN1 (0.38) | FFAR4TSHRMAPTHPGDALDH1A1 | |
| SCHEMBL3913171 | 0.82 | NAMPT (0.34) | TSHRMAPTHPGDALDH1A1F2 | |
| SCHEMBL2933353 | 0.77 | RAB9A (0.42) | FFAR4MAPTHPGDALDH1A1POLB | |
| SCHEMBL3911302 | 0.76 | KMT2A (0.30) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL3920398 | 0.76 | KMT2A (0.30) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL14414201 | 0.76 | ALOX15 (0.34) | FFAR4TSHRMAPTALDH1A1POLB | |
| SCHEMBL5605247 | 0.73 | MAOB (0.53) | TSHRALDH1A1KMT2A | |
| SCHEMBL2926214 | 0.73 | RAB9A (0.48) | TSHRALDH1A1POLBALOX15SRPK1 | |
| SCHEMBL3912903 | 0.72 | MAPT (0.41) | FFAR4MAPTHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024353-A2 | PYRAZOLE COMPOUNDS | Pfizer Products Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007105058-A2 | PYRAZOLE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |