Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL23524667 | 0.94 | OR51E2 (0.37) | OR51E2TGFBR1 | |
| SCHEMBL15368036 | 0.85 | — | — | |
| SCHEMBL4542292 | 0.85 | — | — | |
| SCHEMBL15368035 | 0.85 | — | — | |
| Methacrylic Acid SCHEMBL890487 | 0.82 | LMNA (0.39) | OR51E2TGFBR1TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL2989895 | 0.82 | LMNA (0.39) | OR51E2TGFBR1TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL25371236 | 0.82 | LMNA (0.39) | OR51E2TGFBR1TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL18043470 | 0.82 | LMNA (0.39) | OR51E2TGFBR1TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL1032214 | 0.82 | TDP1 (0.43) | OR51E2TGFBR1TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL65012 | 0.82 | TDP1 (0.43) | OR51E2TGFBR1TET2TET3TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807182-B1 | A PROCESS FOR IMPROVING MEMBRANES | UNIV BEN GURION (IL) | 2009-02-18 | — | — | EP | disclosed |