Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzotriazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzotriazole SCHEMBL28276294 | 1.00 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2MAPTALDH1A1CHRM1 | |
| Benzotriazole SCHEMBL4948842 | 1.00 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2MAPTALDH1A1CHRM1 | |
| Benzotriazole SCHEMBL28276295 | 1.00 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2MAPTALDH1A1CHRM1 | |
| Benzotriazole SCHEMBL28212495 | 0.94 | NPC1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1CHRM1HPGD | |
| Benzotriazole SCHEMBL9019467 | 0.93 | TDP1 (0.39) | L3MBTL1SMN1; SMN2MAPTALDH1A1CHRM1 | |
| Benzotriazole SCHEMBL1507756 | 0.92 | CHRM1 (0.37) | SMN1; SMN2MAPTALDH1A1CHRM1HPGD | |
| Benzotriazole SCHEMBL2458393 | 0.92 | CYP3A4 (0.41) | L3MBTL1SMN1; SMN2MAPTALDH1A1CHRM1 | |
| Benzotriazole SCHEMBL21629494 | 0.92 | CHRM1 (0.37) | SMN1; SMN2MAPTALDH1A1CHRM1HPGD | |
| Benzotriazole SCHEMBL27661352 | 0.92 | CHRM1 (0.37) | SMN1; SMN2MAPTALDH1A1CHRM1HPGD | |
| Benzotriazole SCHEMBL27976494 | 0.92 | LMNA (0.41) | SMN1; SMN2MAPTALDH1A1CHRM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3140 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000600-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN | BILIX CO LTD (KR) | 2026-01-01 | — | — | US | claimed |
| EP-4552640-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN | Bilix Co., Ltd. (KR) | 2025-05-14 | — | — | EP | claimed |
| CN-119403553-A | Pharmaceutical composition for preventing or treating inflammatory diseases comprising pegylated bilirubin | 株式会社毕丽斯 | 2025-02-07 | — | — | CN | claimed |
| CN-117779125-A | Electroplating liquid medicine applied to large-aperture blind holes and process thereof | 永星化工(上海)有限公司 | 2024-03-29 | — | — | CN | claimed |
| WO-2024010353-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING PEGYLATED BILIRUBIN | 주식회사 빌릭스 | 2024-01-11 | — | — | WO | claimed |
| CN-116657142-A | Composite gas phase rust-resisting film and preparation method thereof | 国网江苏省电力有限公司苏州供电分公司 | 2023-08-29 | — | — | CN | claimed |
| EP-3004287-B1 | COMPOSITIONS AND METHODS FOR SELECTIVELY ETCHING TITANIUM NITRIDE | ENTEGRIS INC (US) | 2021-08-18 | — | — | EP | claimed |
| EP-2964725-B1 | COMPOSITIONS AND METHODS FOR SELECTIVELY ETCHING TITANIUM NITRIDE | ENTEGRIS INC (US) | 2021-06-23 | — | — | EP | claimed |
| CN-112110982-A | Preparation method of protein fixed-point pegylation modification | 科兴生物制药股份有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-108219673-B | A kind of pectination polyamino acid composite antibacterial coating and preparation method thereof | 江苏卓尔医疗器械有限公司 | 2019-08-23 | — | — | CN | claimed |
| WO-2001010450-A1 | TARGETED THROMBOLYTIC AGENTS | IMARX THERAPEUTICS, INC. (US) | 2001-02-15 | — | — | WO | claimed |
| EP-1075281-A2 | POLYOL-IFN-BETA CONJUGATES | Applied Research Systems ARS Holding N.V. (AN) | 2001-02-14 | — | — | EP | claimed |
| WO-2000076641-A1 | COMPOSITE MEMBRANE WITH POLYALKYLENE OXIDE MODIFIED POLYAMIDE SURFACE | THE DOW CHEMICAL COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| EP-1037657-A1 | ALPHA-INTERFERON-POLYMER-CONJUGATES HAVING ENHANCED BIOLOGICAL ACTIVITY AND METHODS OF PREPARING THE SAME | ENZON, INC. (US) | 2000-09-27 | — | — | EP | claimed |
| WO-1999055377-A9 | POLYOL-IFN-BETA CONJUGATES | APPLIED RESEARCH SYSTEMS (NL) | 2000-03-02 | — | — | WO | claimed |
| US-5981709-A | CONJUGATING AN ACID STABLE ALPHA-INTERFERON WITH AN ACTIVATED NON-ANTIGENIC POLYMER IN SOLUTION, ACIDIFYING SOLUTION TO SELECTIVELY CLEAVE LINKAGES THAT REDUCE BIOACTIVITY, ADJUST SOLUTION TO A PHYSIOLOGICAL PH | ENZON, INC. (US) | 1999-11-09 | — | — | US | claimed |
| WO-1999055377-A2 | POLYOL-IFN-BETA CONJUGATES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-11-04 | — | — | WO | claimed |
| WO-1999032140-A1 | ALPHA-INTERFERON-POLYMER-CONJUGATES HAVING ENHANCED BIOLOGICAL ACTIVITY AND METHODS OF PREPARING THE SAME | ENZON, INC. (US) | 1999-07-01 | — | — | WO | claimed |
| EP-0057160-B1 | 2-(2-HYDROXYPHENYL)-BENZOTRIAZOLES, THEIR USE AS ULTRAVIOLET STABILIZERS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | claimed |
| EP-0057160-A1 | 2-(2-Hydroxyphenyl)-benzotriazoles, their use as ultraviolet stabilizers and their preparation | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | claimed |