Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | ILK | Q13418 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909913 | 0.96 | MAPT (0.49) | MAPTLMNAMAPK1HSD17B10ACHE | |
| SCHEMBL9327996 | 0.88 | LMNA (0.53) | MAPTLMNAMAPK1HSD17B10ACHE | |
| SCHEMBL3905204 | 0.88 | NPC1 (0.47) | MAPTLMNAMAPK1HSD17B10ACHE | |
| SCHEMBL3900458 | 0.85 | CASP3 (0.52) | MAPTACHEATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL9326928 | 0.85 | TSHR (0.53) | MAPTLMNAMAPK1HSD17B10NPC1 | |
| SCHEMBL9328298 | 0.84 | ALDH1A1 (0.51) | MAPTLMNAMAPK1HSD17B10NPC1 | |
| SCHEMBL10803715 | 0.84 | MAPT (0.50) | MAPTLMNAMAPK1HSD17B10ACHE | |
| SCHEMBL8022715 | 0.84 | MAPT (0.50) | MAPTLMNAMAPK1HSD17B10ACHE | |
| SCHEMBL3909905 | 0.83 | MAPT (0.53) | MAPTLMNAMAPK1ACHENPC1 | |
| SCHEMBL3899773 | 0.83 | GAA (0.50) | MAPTACHENPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235647-B1 | PROCESS FOR THE MANUFACTURE OF 6,13-DIHYDROQUINACRIDONES AND QUINACRIDONES | BAYER AG (DE) | 1993-09-29 | — | — | EP | claimed |
| US-4812568-A | Process for the preparation of 6,13-dihydroquinacridones and quinacridones | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-14 | — | — | US | claimed |
| EP-0632106-B2 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MFG CO (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-0632106-B1 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MFG CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5817817-A | Process for the production of 2,5-di(arylamino)-3,6-dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0648733-B1 | Process for the preparation of intermediates in the quinacridone synthesis | CHEMIE LINZ GMBH (AT) | 1998-01-21 | — | — | EP | disclosed |
| US-5659036-A | Process for the production of 2,5-di(arylamino)-3,6-dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5659076-A | Process for the production of 2,5-dianilino-terephthalic acids | DSM CHEMIE LINZ GMBH (AT) | 1997-08-19 | — | — | US | disclosed |
| US-5491255-A | Process for the transesterification of dimethyl succinylsuccinate | CHEMIE LINZ GMBH (AT) | 1996-02-13 | — | — | US | disclosed |
| EP-0648733-A2 | Quinacridone synthesis and process for preparation of intermediates | DSM Chemie Linz GmbH (AT) | 1995-04-19 | — | — | EP | disclosed |
| EP-0632106-A1 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0313965-B1 | Process for the manufacture of dihydroquinacridones, of quinacridones and of quinacridone quinones | BASF AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0363756-B1 | METHOD FOR THE PREPARATION OF 2,5-DIARYLAMINO-TEREPHTHALIC ACIDS | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-4981997-A | Process for the preparation of 2,5-diarylaminoterephthalic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4956464-A | Cyclization, dehydrogenation in the vapor phase or solid phase in the presence of an oxidizer | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0313965-A2 | Process for the manufacture of dihydroquinacridones, of quinacridones and of quinacridone quinones | BASF Aktiengesellschaft (DE) | 1989-05-03 | — | — | EP | disclosed |
| US-4812568-A | Process for the preparation of 6,13-dihydroquinacridones and quinacridones | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-14 | — | — | US | disclosed |